Page last updated: 2024-09-03

1,3-dimethylbenzimidazoline-2-thione and 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione

1,3-dimethylbenzimidazoline-2-thione has been researched along with 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione in 1 studies

Compound Research Comparison

Studies
(1,3-dimethylbenzimidazoline-2-thione)
Trials
(1,3-dimethylbenzimidazoline-2-thione)
Recent Studies (post-2010)
(1,3-dimethylbenzimidazoline-2-thione)
Studies
(1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione)
Trials
(1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione)
Recent Studies (post-2010) (1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione)
701701

Protein Interaction Comparison

ProteinTaxonomy1,3-dimethylbenzimidazoline-2-thione (IC50)1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione (IC50)
Phospholipase C, gamma 1Homo sapiens (human)4.537
Apoptotic peptidase activating factor 1Homo sapiens (human)0.079
nuclear receptor corepressor 2 isoform 2Homo sapiens (human)4.691
caspase-9 isoform alpha precursorHomo sapiens (human)0.145
dual specificity protein phosphatase 3Homo sapiens (human)10.2
caspase-3 isoform a preproproteinHomo sapiens (human)0.145
cysteine protease ATG4B isoform aHomo sapiens (human)2.07
peroxisome proliferator-activated receptor gamma isoform 2Homo sapiens (human)4.691
tyrosyl-DNA phosphodiesterase 2Homo sapiens (human)0.21
putative polyprotein0.5913

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Other Studies

1 other study(ies) available for 1,3-dimethylbenzimidazoline-2-thione and 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione

ArticleYear
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016